Micronit Microfluidic Chip and Peripheral Equipment

Our unique combination of micro- and nanotechnologies, different materials, microfluidics and MEMS knowledge and customer application knowhow, enables us to provide our customers with the innovative and sustainable solution they are looking for.

Our offer not only standard chips but also design, development, prototyping and (contract) manufacturing of ISO 9001 and ISO 13485 lab-on-a-chip and MEMS solutions.

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Micronit Microfluidic Chip

Droplet Generators

Microfluidic droplet generators are excellent tools for generating highly reproducible microsized droplets with much higher precision and repeatability compared to conventional methods.

By tuning the relative viscosities, surface tension, and velocities between the dispersed and the continuous phase droplets of almost any size can be created. Oil-in-water (O/W) droplets can be generated directly using the glass chips. Water-in-oil droplets (W/O) are best formed in hydrophobic channels (coated glass). This to prevent droplets from sticking to the channel walls.

Droplet Generators

Fields and applications:

Pharmaceutical industry, Cosmetics, Food industries, Chemical reactions, Therapeutic agent delivery (e.g. controlled drug release), Biomolecule synthesis, Diagnostic chips, Drug discovery (e.g. cell culturing) and more...

Focused Flow Droplet Generator

Focused Flow Droplet Generator

T-shaped Droplet Generator

T-shaped Droplet Generator

Droplet Generator Chip

Product Code Product  
936 Focused flow Droplet Generators(nozzle size 5 µm) Drawing
935 Focused flow Droplet Generators(nozzle size 10 µm) Drawing
877 Focused flow Droplet Generators(nozzle size 50 µm) Drawing
580 Focused flow Droplet Generators(nozzle size 75 µm) Drawing
FC_FFDG.2.50_PACK Focused Flow Droplet Generators (large droplets) Drawing
FC_FFDG.2_PACK Focused flow Droplet Generators Drawing
FC_TSDG.2_PACK T-shaped Droplet Genrators Drawing
FC_TSDG.2_PACK Focused flow Droplet Generators(Coated)
FC_FFDG.C.2.50_PACK Focused Flow Droplet Generators (large droplet, Coated
FC_TSDG.C.2_PACK Focused Flow Droplet Generators (large droplet, Coated)

 

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Microreactor Chip

Product code Product  
756 Microreactors (9.5 μl) Drawing
757 Microreactors (18.7 μl) Drawing
FC_R50.332.3_PACK Microreactors (Thin bottom) Drawing
FC_R50.332.2_PACK Microreactors (0.3 μl)
FC_R150.332.2_PC_PACK PC Microreactors (6 μl)
FC_R150.676.2_PC_PACK PC Microreactors (13 μl)
FC_R150.332.2_COC_PACK COC Microreactors (6 μl)
FC_R150.676.2_COC_PACK COC Microreactors (13 μl)
755 H-Microreactors (2.7 μl) Drawing
FC_H150.015.2_PACK H-Microreactors (1.25 μl)
FC_H150.015.2_PC_PACK PC H-Microreactors (1.25 μl)
FC_H150.015.2_COC_PACK COC H-Microreactors
MR_1507.4_MXQ_01 Microreactors 1507

 

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Micromixers

The mixing of fluids in microfluidics can be performed in various ways. One way is using micromixers with so-called folding flow techniques. Folding flow micromixers consist of a chain of elements. In each element the flow is folded upon itself, decreasing the length scale for mixing and thus reducing the mixing time. Other advantages of micromixers are the reduction of the quantities of fluids involved and stable environmental conditions. Folding flow micromixers are also less sensitive to clogging compared to split and recombine mixers. Micronit offers two types of folding flow Micromixers in the web store, the teardrop and swirl micromixer.

Swirl Micromixers

Swirl Micromixers

Teardrop Micromixers

Teardrop Micromixers

Micromixer Chips

Product Code Product  
FC_SW11_PACK Swirl Micromixers Drawing
FC_TD26_PACK Teardrop Micromixers Drawing

 

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Flow Cells

Our flow cells make excellent tools to sort, count, manipulate and image cells.

The dimensions of the microfluidic channels can be in the same range as cell diameters. This allows single cell sorting and counting.

The superior flatness allows perfect optical imaging, the thin bottom makes it suitable for confocal microscopy.

Standard flow cells are hermetically sealed. But also resealable flow cells are an option.

The resealable flow cells are used when access to the inside of the microfluidic chip is required at some point in time.

For example, for sensing applications the glass surface can be chemically modified using spotting equipment prior to an experiment.

These chips are also suitable as a cell culture platform allowing cells to be harvested at the end of an experiment.

Flow cells(Thin Bottom)
Flow cells(Thin Bottom)

These thin bottom flowcells are ideal for experiments such as cell, particle or DNA imaging. The thin 145 micrometer bottom plate making it suitable for confocal microscopy. Pack of 3 chips.

- If you use the Fluidic Connect 4515 Chip holder it is recommended to use fused silica connections (FC_FS_KIT) with nanoport ferrules in combination with the thin bottom chips.

Resealable(Extended)and Resealable(Straight)
Resealable(Extended) Resealable(Straight)

These resealable flowcells are ideal for experiments were access to the fluidic surfaces is necessary either before, after or before and after performing microfluidic experiments. Application examples are cell culturing, enzyme reaction studies, and sensor integration .We recommend to use the Fluidic Connect Pro Resealable chip holder (article no. 00746) together with the Teflon Connection Kit PRO

Flow Cell Chips

Product Code Product  
FC_FLC50.3_PACK Flow Cells(Thin Bottom) Drawing
740 Resealable(Extended) Drawing
741 Resealable(Straight) Drawing

 

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Cross Channel

Our Cross Channel chips are microfluidic chips with two channels crossing each other.

The Cross Channel chips can be used for capillary electrophoresis.

We also provide Cross Channel chips with a thin bottom plate, making them suitable for confocal microscopy.

Cross Channel Chips

Cross Channel Chips

Cross Channel Chips(Thin Bottom)

Cross Channel Chips (Thin Bottom)

If you use the Fluidic Connect 4515 Chip holder it is recommended to use fused silica connections (FC_FS_KIT) with nanoport ferrules in combination with the thin bottom chips.

Cross Channel Chips

Product Code Product  
FC_X3550CH.2_PACK Cross Channel Chips Drawing
FC_X3550CH.3_PACK Cross  Channel Chips(Thin Bottom) Drawing

 

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Frequently purchased together

Enhanced Oil Recovery(EOR)

To study Thermal, Chemical and Microbial Enhanced Oil Recovery, and their effectiveness, the most accurate way is to use a physical rock. However, the use of rocks has several major drawbacks. Lab-on-a-chip technology makes it possible to create surrogate rocks to conduct experiments. Therefore, Micronit has developed three types of Enhanced Oil Recovery chips together with our leading industrial partners. These chips can be used for research into enhanced oil recovery, reservoir engineering and the environment. The chips in our webstore contain either a uniform, physical or a random rock structure network.

画像:石油増進回収チップ (ユニフォームネットワーク/多孔質形状)

EOR Chips
(uniform network)

画像:石油増進回収チップ (フィジカルロックネットワーク/岩石物性形状)

EOR Chips
(physical rock network)

画像:石油増進回収チップ (ランダムネットワーク/多孔質、岩石物性形状)

EOR Chips
(random network)

Enhanced Oil Recovery (EOR) Chips

Product Code Product
FC_EOR.UN.20.2_PACK EOR Chips (uniform network)
FC_EOR.PR.20.2_PACK EOR Chips (physical rock network)
FC_EOR.RN.20.2_PACK EOR Chips (random network)

 

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Frequently purchased together

Capillary Electrophoresis Chips

Capillary electrophoresis is a separation technique that has been very successful in the analysis of DNA fragments and other biomolecules. In capillary electrophoresis, small amounts of fluids are injected into a separation channel by using plug injection. Substances are separated based on their electrophoretic mobility, which is proportional to their charge to size ratio.                                                                                                                                                    Capillary electrophoresis with microfluidic chips offers advantages over traditional CE. Having an integrated injection structure enables injection of much smaller volumes than would be possible in standard CE.  This means the separation channels can be very short (a few centimeters) for certain applications, which results in much faster analysis. An additional advantage of using chips is that the detection can be integrated in the chip.

画像:T3550 CE Chip Pack

T3550 CE Chip Pack

画像:T8050 CE Chip Pack

T8050 CE Chip Pack

画像:X3550 CE Chip Pack

X3550 CE Chip Pack

画像:X8050 CE Chip Pack

X8050 CE Chip Pack

Capillary Electrophoresis Chips

Product Code Product
CH_T3550_PACK T3550 CE Chip
CH_T8050_PACK T8050 CE Chip
CH_X3550_PACK X3550 CE Chip
CH_X8050_PACK X8050 CE Chip

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Frequently purchased together

Peripheral Equipment

Chip Holders

The Fluidic Connect PRO and the Fluidic Connect 4515 allow users to make fluidic and electrical connections in a user friendly way.  Both the chip holders make it possible to create your own lab-on-chip setup within minutes of time and are durable and robust. The chip holders are also both compatible with standard laboratory equipment such as syringe pumps and upright and inverted microscopes.

The Fluidic Connect PRO is our newest model and it works with a Load ‘n Seal design. This design assures tight connections that can be made in seconds. By using different inserts, the Fluidic Connect PRO easily adapts to chips of different sizes and thicknesses. It is even capable of connecting multiple microfluidic chips at one time. All our standard microfluidic chips fit within the customized chip holder.

Chip Holder Fluidic Connect PRO with 4515 Insert

Chip Holder Fluidic Connect PRO with 4515 Insert

Fluidic Connect PRO (Frame)

Fluidic Connect PRO (Frame)

Chip Holder Fluidic Connect 4515

Chip Holder Fluidic Connect 4515

Connection frame 1507

Connection frame 1507

Fluidic Connect PRO Resealable  (for resealable flow cells)

Fluidic Connect PRO Resealable  (for resealable flow cells)

Fluidic Connect PRO OOC (For organ-on-a-chip)

Fluidic Connect PRO OOC (For organ-on-a-chip)

Fluidic Connect Pro OOC, for 4 chips regular (for organ-on-a-chip)

Fluidic Connect Pro OOC, for 4 chips regular (for organ-on-a-chip)

Chip Holders

Product Code Product
FC_PRO_CH4515 Fluidic Connect Pro with 4515 insert
FC_PRO_CH Fluidic Connect Pro without insert
FC_FC4515 Fluidic Connect 4515
MR_FRAME_1507 Chip holder for microreactor chip 1507
746 Fluidic Connect Pro for resealable
750 Fluidic Connect Pro for Organ-on-a-chip
883 Fluidic Connect Pro for 4 Organ-on-a-chip

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Reference

Connection kit

Our connection kits make it possible to use our microfluidic chips in combination with our microfluidic chipholders and platforms.

We offer different connection kits for our wide range of microfluidic chips. This way each connection kit makes sure your experiment yields the highest possible result.

PEEK Connection Kit PRO

PEEK Connection Kit PRO
Product Code FC_PRO_PK_KIT
Product PEEK Connection Kit PRO
Contents five meter tubing (1/16” OD, 250μm ID),
and 5 FFKM perfluoroelastomer ferrules (Perlast)
Temperature
resistant
Up to 100℃
Material Tubing: PEEK (Polyetheretherketone ),
Ferrules FFKM (perlast)
Use in combination with Fluidic Connect PRO (FC_PRO_CH4515)
Others
  • Advised usage in combination with gasses
  • Re-usable
  • Excellent chemical resistance to a wide range of chemicals
  • PEEK can replace stainless steel tubing in most cases
  • Bio-compatible
  • Excellent steam resistance

 

Electrical Connection Kit PRO

Electrical Connection Kit PRO
Product Code FC_PRO_EL_KIT
Product Electrical Connection Kit PRO
Contents 5 cables with probes and banana plug connector and a set of ferrules
Current rating 3A
Maximum Voltage DC 30V (handless use)
AC 60V (handless use)
Maximum operation temperature 50°C
Contact resistance probe 30mR
Connector type Banana Plug
Cable length 915mm
Color Black
Cable size (AWG) 22
Material Spring probe, housing material: Phosphor Bronze
Spring probe, contact tip material: Beryllium Copper
Spring probe, plating: Gold
Ferrule: FFKM
Use in combination with Fluidic Connect PRO(FC_PRO_CH4515)

Electrical Connection Kit

Electrical Connection Kit
Product Code FC_EL_KIT
Product Electrical Connection Kit
Contents 5 cables with probes and banana plug connector and a set of ferrules
Maximum Voltage DC 30 V
AC 60 V
Maximum operation temperature -
Connector typ Banana Plug
Material Cables: beryllium copper, plating (rhodium over nickel), Ferrules: FFKM (Perlast) perfluoroelastome
Use in combination with Fluidic Connect 4515 Chip Holder (FC_FC4515)

Teflon Connection Kit PRO

Teflon Connection Kit PRO
Product Code FC_PRO_TF _KIT
Product Teflon Connection Kit PRO
Contents five meter capillaries (1/16” OD, 250 μm ID),
and 5 FFKM (Perlast) perfluoroelastomer ferrules
High temperature resistant Up to 260℃
Other
  • Re-usable
  • Excellent chemical resistance to a wide range of chemicals
  • Excellent steam resistance
  • Low friction
Use in combination with Chip Holder Fluidic Connect PRO (FC_PRO_CH4515)

 

Teflon Connection Kit

Teflon Connection Kit
Product Code FC_TF_KIT
Product Teflon Connection Kit
Contents five meter capillaries (1/16” OD, 250 μm ID), five ferrules, and nuts
Use in combination with Chip Holder Fluidic Connect 4515 chipholder (FC_FC4515)

 

Stainless Connection Kit

Stainless Connection Kit
Product Code FC_SS_KIT
Product Stainless Connection Kit
Contents five pieces of 50 cm tubing (1/16” OD, 250 μm ID), five ferrules, and nuts.
Other Ideal for experiments where a solid connection
Use in combination with Chip Holder Fluidic Connect 4515 (FC_FC4515)

 

Tube Pump Connection Kit

Tube Pump Connection Kit
Product Code FC_CO_KIT
Product Tube Pump Connection Kit
Contents - Adaptor 10-32 Female to Female Luer, PEEK natural 2x
- Union (thru hole 250µm) for 10-32 male connectors, PEEK black 2x
- Flanged 10-32 connectors, PEEK natural (use with PEEK or ETFE replacement ferrules) 4x
- Replacement ferrules for 10-32 connector, PEEK natural (advised for 1/16" ETFE tubes) 4x
- Replacement ferrules for 10-32 connector, ETFE (advised for fused silica capillary with sleeve) 4x
- Sleeves 1/16" OD for fused silica capillary (340-380OD), FEP green 5x
- Plug for 10-32 female port, Acetal white 2x
- Flangeless 1/4-28 connectors, PEEK natural (use with PEEK or ETFE replacement ferrules) 2x
- Replacement ferrules for 1/4-28 connectors, ETFE blue 2x
- Cap for 1/4-28 connector, ETFE black 2x
To be used for 375 μm OD フューズドシリカ, 1/16 inch テフロン、ステンレスチューブ

 

Connection Kit 1507

Connection Kit 1507
Product Code MR_KIT_TF
Product Connection Kit 1507
Contents 1.5 meter teflon tubing (1/4'' - 28 UNF), five ferrules, and five nuts.
Use in combination with Microreactor 1507

 

Connection Kit PRO for Organ-on-a-chip

Connection Kit PRO for Organ-on-a-chip
Product Code 00943
Product Connection Kit PRO for Organ-on-a-chip
Contents 15 meter capillaries (OD1/16 inch, ID 250 µm), and 20 FFKM (Perlast) perfluoroelastomer ferrules.
Other ・Re-usable
・Excellent chemical resistance to a wide range of chemicals
・excellent steam resistance
・low friction
Use in combination with Fluidic Connect Pro OOC, 4xOrgan-on-a-chip (no. 00883)

 

In-line filters

The filter element can be cleaned.Usage of a filter is recommended to prevent blockage of the channels by small particles, especially for the droplet generators.

In-line filters
Product Code FC_FILTERS
Product In-line filters
Contents 2 filters, 4 connectors
Material PEEK
Compatible to tubing with diameter 1/16” OD (PTFE tubing)

 

Microfluidic platforms

Microfluidic Starter Kit

he portable microfluidic starter kit is developed particularly for the above-mentioned situations. It contains everything you need to conduct microfluidic experiments with standard or custom made microfluidic devices. Whether you want to mix, create droplets or perform a micro-reaction, there is always a chip available. For the selection of your chips you have our extended range of microfluidic chips at your disposal. You can choose up to three chip packs. This can be three of the same or three different packs, the choice is up to you.

Contents microfluidic starter kit:
3 packs of microfluidic chips of your choice
1 Fluidic Connect PRO chip holder
2 Syringe pumps
Accessories (e.g. tubes, nuts and ferrules and manuals)

Microfluidic Starter Kit 1
Microfluidic Starter Kit 2

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Reference

Sideconnect Platforms

The sideconnect starter kit 15 mm x 15 mm enables a fast, easy and robust connection of 15 mm x 15 mm chips. The position of the tube-chip connection on the edge of the chip allows a smooth flow with less bubbles and requires less reagents. The design of the body grants a large viewing area and is compatible with upright and inverted microscopes. The mounting frame and assembly tool keeps the body and connectors in place during assembly of the chip and the interface with the tubing. Accessories can be stored in the build-in storage box of the assembly tool.

Besides ordering standard Micronit chips (coming soon) that fit into the sideconnect holder you can also order your own 15 mm x 15 mm chips.

Why using sideconnect?
Planar interfacing of tubing with chips offers a smooth flow without shear stress.
Small dead volumes at inlets and outlets minimise reagent amounts required.
Dimensions are compatible with upcoming international microfluidics design standards which make exchange of other industrial microfluidic devices possible.
Autoclavable and easy mounting which makes it suitable for applications that require a sterile flow system, i.e. cell culture.

Sideconnect starter kit 15 mm x 15 mm

Sideconnect starter kit 15 mm x 15 mm

Sideconnect starter kit 15 mm x 30 mm

Sideconnect starter kit 15 mm x 30 mm

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Service

Prototyping, Product development, Manufacturing

The development of a successful microfluidic or MEMS device starts with a good and reliable design, suitable for manufacturing and with the shortest possible time to market. And that is something we are good at. Over the years we have helped industrial customers bring successful, next generation products to market especially products in the medical and life science research technology field.

Together with you, our specialists and engineers will create a tailored design that meets your requirements, taking functionality, scalability and cost into consideration. In order to do so, our multidisciplinary team would like to start a true partnership with your development team, to achieve your goals in the most efficient and reliable matter.

Process

Identifying your design requirements

Our team will start by identifying your design requirements and fabrication strategy, so that they can tailor the solution to your needs.

An agile design process

Then an agile design process starts within the Micronit R&D team. The team will select the appropriate materials for your design, staying within your budgetary guidelines.

Design and prototype testing

Next up is design and prototype testing, if necessary followed by the implementation of reiterations.

Transfer to manufacturing

This stage includes the assembly and packaging of commercial products. Quality control and assurance measurements are embedded in accordance to ISO 9001 and ISO 13485 directives, such as Statistical Process Control and traceability procedures.