"Micronit" Microfluidic Chip and Peripheral Equipment
Our unique combination of micro- and nanotechnologies, different materials, microfluidics and MEMS knowledge and customer application knowhow, enables us to provide our customers with the innovative and sustainable solution they are looking for.
Our offer not only standard chips but also design, development, prototyping and (contract) manufacturing of ISO 9001 and ISO 13485 lab-on-a-chip and MEMS solutions.
Micronit Microfluidic Chip
Droplet Generators
Microfluidic droplet generators are excellent tools for generating highly reproducible microsized droplets with much higher precision and repeatability compared to conventional methods.
By tuning the relative viscosities, surface tension, and velocities between the dispersed and the continuous phase droplets of almost any size can be created. Oil-in-water (O/W) droplets can be generated directly using the glass chips. Water-in-oil droplets (W/O) are best formed in hydrophobic channels (coated glass). This to prevent droplets from sticking to the channel walls.
Fields and applications:
Pharmaceutical industry, Cosmetics, Food industries, Chemical reactions, Therapeutic agent delivery (e.g. controlled drug release), Biomolecule synthesis, Diagnostic chips, Drug discovery (e.g. cell culturing) and more...
Focused Flow Droplet Generator
T-shaped Droplet Generator
Droplet Generator Chip
| Product Code | Product | |
|---|---|---|
| 935 | Focused flow Droplet Generators(nozzle size 10 µm) | Drawing |
| 877 | Focused flow Droplet Generators(nozzle size 50 µm) | Drawing |
| 580 | Focused flow Droplet Generators(nozzle size 75 µm) | Drawing |
| FC_FFDG.2.50_PACK | Focused Flow Droplet Generators (large droplets) | Drawing |
| FC_FFDG.2_PACK | Focused flow Droplet Generators | Drawing |
| FC_TSDG.2_PACK | T-shaped Droplet Genrators | Drawing |
| FC_TSDG.2_PACK | Focused flow Droplet Generators(Coated) |
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| FC_FFDG.C.2.50_PACK | Focused Flow Droplet Generators (large droplet, Coated |
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| FC_TSDG.C.2_PACK | Focused Flow Droplet Generators (large droplet, Coated) |
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Frequently purchased together
Reference
Microreactor Chip
| Product code | Product | |
|---|---|---|
| 756 | Microreactors (9.5 μl) | Drawing |
| 757 | Microreactors (18.7 μl) | Drawing |
| FC_R50.332.3_PACK | Microreactors (Thin bottom) | Drawing |
| FC_R50.332.2_PACK | Microreactors (0.3 μl) |
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| FC_R150.332.2_PC_PACK | PC Microreactors (6 μl) |
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| FC_R150.676.2_PC_PACK | PC Microreactors (13 μl) |
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| FC_R150.332.2_COC_PACK | COC Microreactors (6 μl) |
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| FC_R150.676.2_COC_PACK | COC Microreactors (13 μl) |
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| 755 | H-Microreactors (2.7 μl) | Drawing |
| FC_H150.015.2_PACK | H-Microreactors (1.25 μl) |
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| FC_H150.015.2_PC_PACK | PC H-Microreactors (1.25 μl) |
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| FC_H150.015.2_COC_PACK | COC H-Microreactors |
|
| MR_1507.4_MXQ_01 | Microreactors 1507 |
|
Frequently purchased together
Reference
Micromixers
The mixing of fluids in microfluidics can be performed in various ways. One way is using micromixers with so-called folding flow techniques. Folding flow micromixers consist of a chain of elements. In each element the flow is folded upon itself, decreasing the length scale for mixing and thus reducing the mixing time. Other advantages of micromixers are the reduction of the quantities of fluids involved and stable environmental conditions. Folding flow micromixers are also less sensitive to clogging compared to split and recombine mixers. Micronit offers two types of folding flow Micromixers in the web store, the teardrop and swirl micromixer.
Swirl Micromixers
Teardrop Micromixers
Micromixer Chips
| Product Code | Product | |
|---|---|---|
| FC_SW11_PACK | Swirl Micromixers | Drawing |
| FC_TD26_PACK | Teardrop Micromixers | Drawing |
Frequently purchased
Reference
Flow Cells
Our flow cells make excellent tools to sort, count, manipulate and image cells.
The dimensions of the microfluidic channels can be in the same range as cell diameters. This allows single cell sorting and counting.
The superior flatness allows perfect optical imaging, the thin bottom makes it suitable for confocal microscopy.
Standard flow cells are hermetically sealed. But also resealable flow cells are an option.
The resealable flow cells are used when access to the inside of the microfluidic chip is required at some point in time.
For example, for sensing applications the glass surface can be chemically modified using spotting equipment prior to an experiment.
These chips are also suitable as a cell culture platform allowing cells to be harvested at the end of an experiment.
These thin bottom flowcells are ideal for experiments such as cell, particle or DNA imaging. The thin 145 micrometer bottom plate making it suitable for confocal microscopy. Pack of 3 chips.
- If you use the Fluidic Connect 4515 Chip holder it is recommended to use fused silica connections (FC_FS_KIT) with nanoport ferrules in combination with the thin bottom chips.
These resealable flowcells are ideal for experiments were access to the fluidic surfaces is necessary either before, after or before and after performing microfluidic experiments. Application examples are cell culturing, enzyme reaction studies, and sensor integration .We recommend to use the Fluidic Connect Pro Resealable chip holder (article no. 00746) together with the Teflon Connection Kit PRO
Flow Cell Chips
| Product Code | Product | |
|---|---|---|
| FC_FLC50.3_PACK | Flow Cells（Thin Bottom） | Drawing |
| 740 | Resealable（Extended） | Drawing |
| 741 | Resealable（Straight） | Drawing |
Frequently purchased together
Reference
Cross Channel
Our Cross Channel chips are microfluidic chips with two channels crossing each other.
The Cross Channel chips can be used for capillary electrophoresis.
We also provide Cross Channel chips with a thin bottom plate, making them suitable for confocal microscopy.
Cross Channel Chips
Cross Channel Chips (Thin Bottom)
If you use the Fluidic Connect 4515 Chip holder it is recommended to use fused silica connections (FC_FS_KIT) with nanoport ferrules in combination with the thin bottom chips.
Cross Channel Chips
| Product Code | Product | |
|---|---|---|
| FC_X3550CH.2_PACK | Cross Channel Chips | Drawing |
| FC_X3550CH.3_PACK | Cross Channel Chips（Thin Bottom） | Drawing |
Frequently purchased together
Enhanced Oil Recovery(EOR)
To study Thermal, Chemical and Microbial Enhanced Oil Recovery, and their effectiveness, the most accurate way is to use a physical rock. However, the use of rocks has several major drawbacks. Lab-on-a-chip technology makes it possible to create surrogate rocks to conduct experiments. Therefore, Micronit has developed three types of Enhanced Oil Recovery chips together with our leading industrial partners. These chips can be used for research into enhanced oil recovery, reservoir engineering and the environment. The chips in our webstore contain either a uniform, physical or a random rock structure network.
EOR Chips
(uniform network)
EOR Chips
(physical rock network)
EOR Chips
(random network)
Enhanced Oil Recovery (EOR) Chips
| Product Code | Product |
|---|---|
| FC_EOR.UN.20.2_PACK | EOR Chips (uniform network) |
| FC_EOR.PR.20.2_PACK | EOR Chips (physical rock network) |
| FC_EOR.RN.20.2_PACK | EOR Chips (random network) |
Frequently purchased together
Capillary Electrophoresis Chips
Capillary electrophoresis is a separation technique that has been very successful in the analysis of DNA fragments and other biomolecules. In capillary electrophoresis, small amounts of fluids are injected into a separation channel by using plug injection. Substances are separated based on their electrophoretic mobility, which is proportional to their charge to size ratio. Capillary electrophoresis with microfluidic chips offers advantages over traditional CE. Having an integrated injection structure enables injection of much smaller volumes than would be possible in standard CE. This means the separation channels can be very short (a few centimeters) for certain applications, which results in much faster analysis. An additional advantage of using chips is that the detection can be integrated in the chip.
T3550 CE Chip Pack
T8050 CE Chip Pack
X3550 CE Chip Pack
X8050 CE Chip Pack
Capillary Electrophoresis Chips
| Product Code | Product |
|---|---|
| CH_T3550_PACK | T3550 CE Chip |
| CH_T8050_PACK | T8050 CE Chip |
| CH_X3550_PACK | X3550 CE Chip |
| CH_X8050_PACK | X8050 CE Chip |
Frequently purchased together
Peripheral Equipment
Chip Holders
The Fluidic Connect PRO and the Fluidic Connect 4515 allow users to make fluidic and electrical connections in a user friendly way. Both the chip holders make it possible to create your own lab-on-chip setup within minutes of time and are durable and robust. The chip holders are also both compatible with standard laboratory equipment such as syringe pumps and upright and inverted microscopes.
The Fluidic Connect PRO is our newest model and it works with a Load ‘n Seal design. This design assures tight connections that can be made in seconds. By using different inserts, the Fluidic Connect PRO easily adapts to chips of different sizes and thicknesses. It is even capable of connecting multiple microfluidic chips at one time. All our standard microfluidic chips fit within the customized chip holder.
Chip Holder Fluidic Connect PRO with 4515 Insert
Fluidic Connect PRO (Frame)
Chip Holder Fluidic Connect 4515
Connection frame 1507
Fluidic Connect PRO Resealable (for resealable flow cells)
Fluidic Connect PRO OOC (For organ-on-a-chip)
Fluidic Connect Pro OOC, for 4 chips regular (for organ-on-a-chip)
Chip Holders
| Product Code | Product |
|---|---|
| FC_PRO_CH4515 | Fluidic Connect Pro with 4515 insert |
| FC_PRO_CH | Fluidic Connect Pro without insert |
| FC_FC4515 | Fluidic Connect 4515 |
| MR_FRAME_1507 | Chip holder for microreactor chip 1507 |
| 746 | Fluidic Connect Pro for resealable |
| 750 | Fluidic Connect Pro for Organ-on-a-chip |
| 883 | Fluidic Connect Pro for 4 Organ-on-a-chip |
Reference
Connection kit
Our connection kits make it possible to use our microfluidic chips in combination with our microfluidic chipholders and platforms.
We offer different connection kits for our wide range of microfluidic chips. This way each connection kit makes sure your experiment yields the highest possible result.
PEEK Connection Kit PRO
| Product Code | FC_PRO_PK_KIT |
|---|---|
| Product | PEEK Connection Kit PRO |
| Contents | five meter tubing (1/16” OD, 250μm ID), and 5 FFKM perfluoroelastomer ferrules (Perlast) |
| Temperature resistant |
Up to 100℃ |
| Material | Tubing: PEEK (Polyetheretherketone ), Ferrules FFKM (perlast) |
| Use in combination with | Fluidic Connect PRO (FC_PRO_CH4515) |
| Others |
|
Electrical Connection Kit PRO
| Product Code | FC_PRO_EL_KIT |
|---|---|
| Product | Electrical Connection Kit PRO |
| Contents | 5 cables with probes and banana plug connector and a set of ferrules |
| Current rating | ３A |
| Maximum Voltage DC | 30V (handless use) |
| AC | 60V (handless use) |
| Maximum operation temperature | 50°C |
| Contact resistance probe | 30mR |
| Connector type | Banana Plug |
| Cable length | 915mm |
| Color | Black |
| Cable size (AWG) | 22 |
| Material | Spring probe, housing material: Phosphor Bronze Spring probe, contact tip material: Beryllium Copper Spring probe, plating: Gold Ferrule: FFKM |
| Use in combination with | Fluidic Connect PRO(FC_PRO_CH4515) |
Electrical Connection Kit
| Product Code | FC_EL_KIT |
|---|---|
| Product | Electrical Connection Kit |
| Contents | 5 cables with probes and banana plug connector and a set of ferrules |
| Maximum Voltage DC | 30 V |
| AC | 60 V |
| Maximum operation temperature | - |
| Connector typ | Banana Plug |
| Material | Cables: beryllium copper, plating (rhodium over nickel), Ferrules: FFKM (Perlast) perfluoroelastome |
| Use in combination with | Fluidic Connect 4515 Chip Holder (FC_FC4515) |
Teflon Connection Kit PRO
| Product Code | FC_PRO_TF _KIT |
|---|---|
| Product | Teflon Connection Kit PRO |
| Contents | five meter capillaries (1/16” OD, 250 μm ID), and 5 FFKM (Perlast) perfluoroelastomer ferrules |
| High temperature resistant | Up to 260℃ |
| Other |
|
| Use in combination with | Chip Holder Fluidic Connect PRO (FC_PRO_CH4515) |
Teflon Connection Kit
| Product Code | FC_TF_KIT |
|---|---|
| Product | Teflon Connection Kit |
| Contents | five meter capillaries (1/16” OD, 250 μm ID), five ferrules, and nuts |
| Use in combination with | Chip Holder Fluidic Connect 4515 chipholder (FC_FC4515) |
Stainless Connection Kit
| Product Code | FC_SS_KIT |
|---|---|
| Product | Stainless Connection Kit |
| Contents | five pieces of 50 cm tubing (1/16” OD, 250 μm ID), five ferrules, and nuts. |
| Other | Ideal for experiments where a solid connection |
| Use in combination with | Chip Holder Fluidic Connect 4515 (FC_FC4515) |
Tube Pump Connection Kit
| Product Code | FC_CO_KIT |
|---|---|
| Product | Tube Pump Connection Kit |
| Contents | - Adaptor 10-32 Female to Female Luer, PEEK natural 2x - Union (thru hole 250µm) for 10-32 male connectors, PEEK black 2x - Flanged 10-32 connectors, PEEK natural (use with PEEK or ETFE replacement ferrules) 4x - Replacement ferrules for 10-32 connector, PEEK natural (advised for 1/16" ETFE tubes) 4x - Replacement ferrules for 10-32 connector, ETFE (advised for fused silica capillary with sleeve) 4x - Sleeves 1/16" OD for fused silica capillary (340-380OD), FEP green 5x - Plug for 10-32 female port, Acetal white 2x - Flangeless 1/4-28 connectors, PEEK natural (use with PEEK or ETFE replacement ferrules) 2x - Replacement ferrules for 1/4-28 connectors, ETFE blue 2x - Cap for 1/4-28 connector, ETFE black 2x |
| To be used for | 375 μm OD フューズドシリカ, 1/16 inch テフロン、ステンレスチューブ |
Connection Kit 1507
| Product Code | MR_KIT_TF |
|---|---|
| Product | Connection Kit 1507 |
| Contents | 1.5 meter teflon tubing (1/4'' - 28 UNF), five ferrules, and five nuts. |
| Use in combination with | Microreactor 1507 |
Connection Kit PRO for Organ-on-a-chip
| Product Code | 00943 |
|---|---|
| Product | Connection Kit PRO for Organ-on-a-chip |
| Contents | 15 meter capillaries (OD1/16 inch, ID 250 µm), and 20 FFKM (Perlast) perfluoroelastomer ferrules. |
| Other | ・Re-usable ・Excellent chemical resistance to a wide range of chemicals ・excellent steam resistance ・low friction |
| Use in combination with | Fluidic Connect Pro OOC, 4ｘOrgan-on-a-chip (no. 00883) |
In-line filters
The filter element can be cleaned.Usage of a filter is recommended to prevent blockage of the channels by small particles, especially for the droplet generators.
| Product Code | FC_FILTERS |
|---|---|
| Product | In-line filters |
| Contents | 2 filters, 4 connectors |
| Material | PEEK |
| Compatible to tubing with diameter | 1/16” OD (PTFE tubing) |
Microfluidic platforms
Microfluidic Starter Kit
he portable microfluidic starter kit is developed particularly for the above-mentioned situations. It contains everything you need to conduct microfluidic experiments with standard or custom made microfluidic devices. Whether you want to mix, create droplets or perform a micro-reaction, there is always a chip available. For the selection of your chips you have our extended range of microfluidic chips at your disposal. You can choose up to three chip packs. This can be three of the same or three different packs, the choice is up to you.
Contents microfluidic starter kit:
3 packs of microfluidic chips of your choice
1 Fluidic Connect PRO chip holder
2 Syringe pumps
Accessories (e.g. tubes, nuts and ferrules and manuals)
Reference
Sideconnect Platforms
The sideconnect starter kit 15 mm x 15 mm enables a fast, easy and robust connection of 15 mm x 15 mm chips. The position of the tube-chip connection on the edge of the chip allows a smooth flow with less bubbles and requires less reagents. The design of the body grants a large viewing area and is compatible with upright and inverted microscopes. The mounting frame and assembly tool keeps the body and connectors in place during assembly of the chip and the interface with the tubing. Accessories can be stored in the build-in storage box of the assembly tool.
Besides ordering standard Micronit chips (coming soon) that fit into the sideconnect holder you can also order your own 15 mm x 15 mm chips.
Why using sideconnect?
Planar interfacing of tubing with chips offers a smooth flow without shear stress.
Small dead volumes at inlets and outlets minimise reagent amounts required.
Dimensions are compatible with upcoming international microfluidics design standards which make exchange of other industrial microfluidic devices possible.
Autoclavable and easy mounting which makes it suitable for applications that require a sterile flow system, i.e. cell culture.
Sideconnect starter kit 15 mm x 15 mm
Sideconnect starter kit 15 mm x 30 mm
Service
Prototyping, Product development, Manufacturing
The development of a successful microfluidic or MEMS device starts with a good and reliable design, suitable for manufacturing and with the shortest possible time to market. And that is something we are good at. Over the years we have helped industrial customers bring successful, next generation products to market especially products in the medical and life science research technology field.
Together with you, our specialists and engineers will create a tailored design that meets your requirements, taking functionality, scalability and cost into consideration. In order to do so, our multidisciplinary team would like to start a true partnership with your development team, to achieve your goals in the most efficient and reliable matter.
Process
Identifying your design requirements
Our team will start by identifying your design requirements and fabrication strategy, so that they can tailor the solution to your needs.
An agile design process
Then an agile design process starts within the Micronit R&D team. The team will select the appropriate materials for your design, staying within your budgetary guidelines.
Design and prototype testing
Next up is design and prototype testing, if necessary followed by the implementation of reiterations.
Transfer to manufacturing
This stage includes the assembly and packaging of commercial products. Quality control and assurance measurements are embedded in accordance to ISO 9001 and ISO 13485 directives, such as Statistical Process Control and traceability procedures.